Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure – DOI: 10.1126/science.abq1841
A team of 19 UK scientists from Imperial College of London, London School of Medicine have published new research that helps explain why countries with the highest vaccination rates are experiencing the highest numbers of what they call “emerging infections” as well as reinfection with other COVID-19 variants.
This research article, published June 14, 2022 in the peer-reviewed journal Science, was downloaded nearly 277,500 times in less than two months. That is highly unusual for a densely written, highly technical scientific study.
This study suggests, on what many physicians and research scientists have already expressed and that is that mRNA injections against COVID-19, as well as booster injections, may be making our immune response less effective against the Omicron variant of the virus.
If this is correct, it means that the injection itself is causing widespread infection. Instead of stopping the virus, it appears that mRNA vaccination programs around the world may have inadvertently made the virus more ubiquitous, i.e. present everywhere at the same time.
The more injections, the higher the infection rates.
As the British scientists point out, countries with higher injection uptake rates are experiencing large numbers of primary infections and frequent reinfections with SARS-CoV-2.
In contrast, in places where vaccination campaigns have not been widely implemented, including most countries on the African continent, people are not becoming infected.
In analyzing why the most vaccinated populations get the most Omicron infections, this study focused on the most vaccinated professionals: medical personnel who had received the two doses of mRNA injections from the start and then received two booster injections twice more. To find out what was happening at the cellular level with these highly vaccinated health care workers, the scientists closely followed the different types of immunoglobin in the participants’ blood.
Immunoglobin (Ig), also known as antibody (Ab), finds viruses, bacteria and others, and causes the immune system to respond appropriately.
Scientists have identified several types of immunoglobulins, each of which guides the immune response differently for different phases and types of infection.
IgG4 is the form of immunoglobulin that triggers a tolerance response in the immune system for things it has been repeatedly exposed to and does not need to generate an inflammatory response. This is good if you are trying to avoid immune sensitivity to a food, for example. But it’s not the type of immune response that COVID-19 injections were designed for.
Beekeepers, when repeatedly stung by bees throughout their career, mount an IgG4 response to the attack on their immune systems. Basically, their bodies learn that bee venom is not dangerous and their immune response to bee venom becomes an IgG4 response, so they can tolerate the stings very well. While the bee venom itself will not harm the body, the body’s own inflammatory response can be dangerous. If the body overreacts and develops a generalized response in which the inflammation itself endangers a person’s breathing, the immune response can be lethal.
This study demonstrates exactly how repeated injections are causing people to become more susceptible to COVID-19. The initial doses of the injection elicited classic inflammatory immune responses. Inflammation is a fundamental part of an immune response (to a vaccine, injection or infection), and is responsible for most of what you feel when you are sick: fever, aches, pains, lethargy, etc. This inflammation is the reason you may feel sick, the COVID-19 injection has become famous for making people feel so sick for a few days. Your body is producing an inflammatory response to the proteins.
But what happens in the body after you’ve had two injections and then you get a third? The scientists discovered that successive doses of the mRNA injections begin to habituate or desensitize subjects to the peak proteins, migrating their immune response to be dominated by the IgG4 form, which essentially teaches the body to tolerate the proteins.
There was no longer a response to the injection in the COVID-19 participants, making them even more vulnerable to infection and less likely to generate a response than those who had never been vaccinated.
When you are exposed to a cold or any other virus repeatedly, spaced out over a lifetime, which is what happens with natural exposure, you don’t build up a tolerance, your body fights it off without you even realizing it. The body is using the normal immune response to fight disease but, because it recognizes the infectious agent, it has no symptoms of inflammation. This is why when you are naturally exposed to many diseases, you have lifelong immunity.
In contrast, this new study shows that repeated mRNA injections and boosters for COVID-19 are producing a tolerance response. They are habituating the body to the virus, so that you no longer recognize it as dangerous.
Another study, published in July by a team of more than 20 German scientists, independently confirmed that successive COVID-19 injections and boosters were converting the immune response from the protective IgG response class to the tolerance class.
So, the injection and booster program ended up doing the opposite of what it was intended to do: prevent people from getting sick.
On the one hand, this study suggests that the injections are helping the body’s immune system not to react strongly to the virus. The virus itself was not killing people: it was the interaction of the virus with the patients’ immune systems that caused severe and sometimes lethal infections, as the immune system overreacted to a new virus.
On the other hand, naturally acquired immunity is stronger than immunity acquired by injection, and the dangers of the injections themselves, especially for the young, suggest that the risks of vaccination far outweigh the benefits.
Booster injections were never necessary to produce tolerance: the study showed that subjects began to develop tolerance after only two doses. There is no need to continue with successive boosters….
The adverse effects of COVID injections were confirmed by the European Medicines Agency (EMA), which warned that frequent COVID injection boosters could adversely affect immune responses to the virus. The agency said booster doses should be spaced beyond every four months.
The head of the EMA’s office of biological health threats and injection strategy, Marco Cavaleri, PhD, cautioned:
Rather, we are concerned about a strategy that entangles repeated vaccinations in a short time frame. We can’t really give booster doses continuously every 3-4 months…There are two concerns here: if we have a strategy where we give boosters, say, every four months or so, we will end up having potential problems with the immune response, and the immune response may not be as good as we would like it to be. So we have to be careful not to overload the immune system with repeated immunizations. “And secondly, there is a risk of population fatigue with the continuous administration of boosters.”
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